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The figure shows the p -values of terms in the basic MLR models predicting mean carvedilol release. The dynamic changes in these p -values over the release interval reflect shifting term significance, with lower p -values indicating stronger effects. Conventionally, p ≤ 0.05 ( α = 0.05) denotes statistical significance. The green background indicates the main interpretation range of the models.

Journal: Pharmaceutics

Article Title: Influence of Selected Hypromellose Functionality-Related Characteristics and Soluble/Insoluble Filler Ratio on Carvedilol Release from Matrix Tablets

doi: 10.3390/pharmaceutics17101358

Figure Lengend Snippet: The figure shows the p -values of terms in the basic MLR models predicting mean carvedilol release. The dynamic changes in these p -values over the release interval reflect shifting term significance, with lower p -values indicating stronger effects. Conventionally, p ≤ 0.05 ( α = 0.05) denotes statistical significance. The green background indicates the main interpretation range of the models.

Article Snippet: More detailed information on the generated MLR models for mean % and SD of carvedilol release at each time point is provided in the , and Minitab ® reports.

Techniques:

Percentage contribution of terms in the basic MLR models predicting mean carvedilol release. Changes in these contributions over the release interval indicate shifting term importance—higher percentages denote greater influence. The green background indicates the main interpretation range of the models.

Journal: Pharmaceutics

Article Title: Influence of Selected Hypromellose Functionality-Related Characteristics and Soluble/Insoluble Filler Ratio on Carvedilol Release from Matrix Tablets

doi: 10.3390/pharmaceutics17101358

Figure Lengend Snippet: Percentage contribution of terms in the basic MLR models predicting mean carvedilol release. Changes in these contributions over the release interval indicate shifting term importance—higher percentages denote greater influence. The green background indicates the main interpretation range of the models.

Article Snippet: More detailed information on the generated MLR models for mean % and SD of carvedilol release at each time point is provided in the , and Minitab ® reports.

Techniques:

The figure shows the p -values of terms in the optimized MLR models predicting mean carvedilol release. The dynamic changes in these p -values over the release interval reflect shifting term significance, with lower p -values indicating stronger effects. Conventionally, p ≤ 0.05 (α = 0.05) denotes statistical significance. The green background indicates the main interpretation range of the models.

Journal: Pharmaceutics

Article Title: Influence of Selected Hypromellose Functionality-Related Characteristics and Soluble/Insoluble Filler Ratio on Carvedilol Release from Matrix Tablets

doi: 10.3390/pharmaceutics17101358

Figure Lengend Snippet: The figure shows the p -values of terms in the optimized MLR models predicting mean carvedilol release. The dynamic changes in these p -values over the release interval reflect shifting term significance, with lower p -values indicating stronger effects. Conventionally, p ≤ 0.05 (α = 0.05) denotes statistical significance. The green background indicates the main interpretation range of the models.

Article Snippet: More detailed information on the generated MLR models for mean % and SD of carvedilol release at each time point is provided in the , and Minitab ® reports.

Techniques:

Percentage contribution of terms in the optimized MLR models predicting mean carvedilol release. Changes in these contributions over the release interval indicate shifting term importance—higher percentages denote greater influence. The green background indicates the main interpretation range of the models.

Journal: Pharmaceutics

Article Title: Influence of Selected Hypromellose Functionality-Related Characteristics and Soluble/Insoluble Filler Ratio on Carvedilol Release from Matrix Tablets

doi: 10.3390/pharmaceutics17101358

Figure Lengend Snippet: Percentage contribution of terms in the optimized MLR models predicting mean carvedilol release. Changes in these contributions over the release interval indicate shifting term importance—higher percentages denote greater influence. The green background indicates the main interpretation range of the models.

Article Snippet: More detailed information on the generated MLR models for mean % and SD of carvedilol release at each time point is provided in the , and Minitab ® reports.

Techniques:

The figure shows the p -values of terms in the optimized MLR models predicting SD of carvedilol release. The dynamic changes in these p -values over the release interval reflect shifting term significance—with lower p -values indicating stronger effects. Conventionally, p ≤ 0.05 (α = 0.05) denotes statistical significance. The green background indicates the main interpretation range of the models.

Journal: Pharmaceutics

Article Title: Influence of Selected Hypromellose Functionality-Related Characteristics and Soluble/Insoluble Filler Ratio on Carvedilol Release from Matrix Tablets

doi: 10.3390/pharmaceutics17101358

Figure Lengend Snippet: The figure shows the p -values of terms in the optimized MLR models predicting SD of carvedilol release. The dynamic changes in these p -values over the release interval reflect shifting term significance—with lower p -values indicating stronger effects. Conventionally, p ≤ 0.05 (α = 0.05) denotes statistical significance. The green background indicates the main interpretation range of the models.

Article Snippet: More detailed information on the generated MLR models for mean % and SD of carvedilol release at each time point is provided in the , and Minitab ® reports.

Techniques:

Percentage contribution of terms in the optimized MLR models predicting SD of carvedilol release. Changes in these contributions over the release interval indicate shifting term importance—higher percentages denote greater influence. The green background indicates the main interpretation range of the models.

Journal: Pharmaceutics

Article Title: Influence of Selected Hypromellose Functionality-Related Characteristics and Soluble/Insoluble Filler Ratio on Carvedilol Release from Matrix Tablets

doi: 10.3390/pharmaceutics17101358

Figure Lengend Snippet: Percentage contribution of terms in the optimized MLR models predicting SD of carvedilol release. Changes in these contributions over the release interval indicate shifting term importance—higher percentages denote greater influence. The green background indicates the main interpretation range of the models.

Article Snippet: More detailed information on the generated MLR models for mean % and SD of carvedilol release at each time point is provided in the , and Minitab ® reports.

Techniques:

Overview of the main effects and interactions influencing mean carvedilol release across the three phases identified by the optimized MLR models. Fading colours signal effects gradually becoming more important or diminishing with time.

Journal: Pharmaceutics

Article Title: Influence of Selected Hypromellose Functionality-Related Characteristics and Soluble/Insoluble Filler Ratio on Carvedilol Release from Matrix Tablets

doi: 10.3390/pharmaceutics17101358

Figure Lengend Snippet: Overview of the main effects and interactions influencing mean carvedilol release across the three phases identified by the optimized MLR models. Fading colours signal effects gradually becoming more important or diminishing with time.

Article Snippet: More detailed information on the generated MLR models for mean % and SD of carvedilol release at each time point is provided in the , and Minitab ® reports.

Techniques:

Overview of the main effects and interactions influencing SD of carvedilol release across the four phases identified by the optimized MLR models. Fading colours signal effects gradually becoming more important or diminishing with time.

Journal: Pharmaceutics

Article Title: Influence of Selected Hypromellose Functionality-Related Characteristics and Soluble/Insoluble Filler Ratio on Carvedilol Release from Matrix Tablets

doi: 10.3390/pharmaceutics17101358

Figure Lengend Snippet: Overview of the main effects and interactions influencing SD of carvedilol release across the four phases identified by the optimized MLR models. Fading colours signal effects gradually becoming more important or diminishing with time.

Article Snippet: More detailed information on the generated MLR models for mean % and SD of carvedilol release at each time point is provided in the , and Minitab ® reports.

Techniques: